|The research was the quasi-experimental study. It aimed to compare the effectiveness of the pharmaceutical care between the pre-intervention period and intervention period, in which the pharmacist was involved at the tuberculosis clinic. The study was evaluated for the process and outcome of the pharmaceutical care; that is, the number of drug related problems, knowledge of the disease and medicines and satisfaction of the patients at the tuberculosis clinic, including the correlations between the personal factors and health behaviors of the patients and drug related problems. The data collection was divided into two parts= one was from the control group comprising of 83 patients performed during October 1, 2006 to September 30, 2007, before the pharmacist’s intervention and the other was from the experimental group comprising of 52 patients performed during October 1, 2007 to June 30, 2008, while a pharmacist performed at the tuberculosis clinic. The data was collected using the questionnaire and the outpatient records. The data was analyzed by using descriptive statistics and comparing means with t-test, Pearson’s chi-square test, One way Anova and Mann Whitney U-test.
According to the result, the pharmacist could indicate drug related problems more efficiently and found a higher number of drug related problems in the experimental group than in the control group with statistical significance (p< 0.05). The average number of the drug related problems per one patient was 7.40 + 2.47 in the experimental group and 0.73 + 0.91 in the control group. From the total of 385 and 61 drug related problems in the experimental and the control groups respectively, the most frequent incidence among the problems was adverse drug reaction (65.4 % and 88.6% in the control and the experimental groups, respectively).All of the drug related problems which were found, 301 of them (78.18 %) were solved. In addition, the average knowledge score of the experimental patients was at a high level (17.04 1.37 from the total score of 20). The total knowledge score of the experimental patients was not correlated to the total drug related problems (r = -0.28, p=0.845). The patients’ satisfaction with the pharmaceutical care service in the aspects of the clinic structure and staff at the tuberculosis clinic was at a high level (the average score being 3.81 0.22 from the total of 5). Moreover, the personal factor which was significantly correlated to the overall drug related problems was the occurrence of tuberculosis in family history. The tuberculosis family history was also correlated to the dispensing of pharmacy problems significantly (U =214.5, p = 0.012). The patients’ behaviors; smoking, alcohol drinking and taking some drugs, was not correlated to the overall drug related problems.
In conclusion, the benefits of the study are for the progress of the pharmacists’ role in pharmaceutical care in cooperation with the interdisciplinary health team which should lead to the increased life quality of the tuberculosis patients at the tuberculosis clinic in Yangchumnoi hospital, Srisaket province.