| This study was aimed to preliminarily study radical scavenging and xanthine oxidase inhibitory activities of 20 select medicinal plant extracts. The studies were composed the antioxidant activity was first investigated using 2,2-diphenyl-1(2,4,6-trinitrophenyl)hydrazyl (DPPH) assay, compared with gallic acid , vitamin C and curcuminoid. The plant extracts giving IC50 less than 100.00 µg/ml were selected to study the anti-xanthine oxidase activity compared allopurinol. The extracts of DischidiarafflesianaWall., Piper betleL., PunicagranatumL., CinnamomuminersReirw., NelumbonuciferaGaerth., BauhinaipenicillilobaPierre., ParinarianamenseHance., Curcuma xanthorrhizaRoxb., PolygoniumodoratumLour., Gratoxylumformosum., Dracaena loureiriGagnep., and MyristicafragransHoutt. showed antioxidant capacity (IC50 < 100.00 µg/ml). Extracts of CinnamomuminersReirw., NelumbonuciferaGaerth., Piper betleL., PolygoniumodoratumLour., and Curcuma xanthorrhizaRoxb inhibited xanthine oxidase activity compared with allopurinol equivalent antixanthine oxidase activity. Other plants also demonstrated antioxidant and xanthine oxidase inhibitory activities although with less extent. Various medicinal plants, possessing antioxidant activity and xanthine oxidase inhibitor, could be a good candidate for future studies of in vivo models of gout. |