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Abstract |
| Title |
: DPPH, PIPER SARMENTOSUM, ENZYME
ACETYLCHOLINESTERASE
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| By |
: Chantima Pannaphon
Rawiwan Kamnon
Nalinee Kinnares |
| Degree |
: BACHELOR OF PHARMACY |
| Advisor |
: Rawiwan Kaewamatawong
Nuttiya Werawattanachai |
| Keywords |
: DPPH, PIPER SARMENTOSUM, ENZYME ACETYLCHOLINESTERASE |
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| The objective of this study was to determine DPPH scavenging and acetylcholinesterase inhibitory activites from crude extracts and isolated fractions of Piper sarmentosum leaves. From the results, methanol extract exhibited the highest activities in both DPPH scavenging and acetylcholinesterase inhibitory activites (64.89 ± 3.84 % and 50.44 ± 2.94 %, respectively). Among the fractions, fraction CPM - 5 from methanol extract showed the highest DPPH scavenging activity at 88.82 ± 1.46 %, while CPE - 2 of ethyl acetate extract showed the highest acetylcholinesterase inhibitory activity at 47.26 ± 3.97 %. Chemical constituents of each extracts were detected by TLC with specific spraying reagents. Hexane extract contained terpenoids. Ethyl acetate and methanol extracts were composed of alkaloids, phenolic compounds and terpenoids. |
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