The aim of this study was to develop gelly formulation of Vernonia Cinerea LESS. for smoking cessation. This study comprises quantitation of active compounds in Vernonia Cinerea LESS. extraction, development of gelly formulation, quantitation of active compounds in formulation, assessment of physical properties, physical and microbial stability assessment of formulation for 1 and 3 months at 4°C, 25°C, and 45 °C kept in 2 different forms as with and without plastic wraps. Moreover, customer satisfaction in formulation was assessed from 33 volunteer. Vernonia Cinerea LESS. was water extracted. Quantitation of total phenol, flavonoid, and nitrate in the extraction is 0.50 1.60 and 1.60 mg/ 1 g of dry herb, respectively. Gelly formulation was developed and the optimum ratio of gellatin=pectin=citric acid=glucose is 28=0.48=0.5=14.3. Quantitation of total phenol, flavonoid, and nitrate in formulation is 1.09, 1.55 และ 1.40 mg per 2 pieces of gelly (1 g of dry herb), respectively. The quantitation of active compounds in formulation was interfered by sedimentation. The average weight of gelly formulation is 3.67 grams/piece. The gelly is physical and microbial stable for 1 and 3 months at 4°C and 25°C with the microbial less than 30 CFU /g and amount of yeast and fungus less than 10 CFU/g. Whereas, the gelly was melted at 45 °C. Customer satisfaction in formulation from 33 volunteer was in good level. This study has developed gelly formulation from extraction of Vernonia Cinerea LESS. for smoking cessation with good physical and stability. However, should study the efficiency of the product in the following smoking cessation. |