Abstract

Development of facial sleeping mask gel

contained Centella asiatica extract

And β-glucan for moisture retention effect

Thanida Nuangchompoo

Nuttacha Jansiri 

Utsana Puapermpoonsiri

Warisada Sila-on

sleeping mask gel_, Centella asiatica,  β-glucan and moisture retention

Introduction: Facial sleeping mask gel is widely used for consumers regarding its easy to apply, non-sticky and cooling effect at applying to the face. To enhance the efficacy of products, the natural moisturizers should be incorporated. Those are the extracts of Centella asiatica which presenting the antioxidant activity and water skin retaining effect of β-glucan. This research aims to develop facial gel sleeping mask contained Centella asiatica extract and β-glucan for skin moisturized retention. Methods: Determine the appropriate type and amount of gelling agent by using polyacrylic acid (Carbomer) and anionic acrylamide copolymer (Himosap Gas 100). The effect of β-glucan concentration on moisture retention capacity by in vitro occlusive test was carried out. In vitro skin irritation test by pH rise of bovine serum albumin and Hen’s Egg Test on the Chorioallantonic Membrane (HET-CAM) was also studied. Results:  All obtained gel bases were clear. The viscosity of the gel base depended on concentration and type of gelling agent. pH values of the gel bases were in the range of 5.2-6.9 and viscosity of 1,439– 46,2830 cP. While pH values of the commercial products were in the range of 5.2-5.5 with the viscosity of 9,552- 13,347 cP. The moisture retention test found that gel formula contained 3 %w/w of β-glucan showed significantly more moisture retention than that of  5 %w/w of β-glucan (p <0.05). No difference in moisture retention capacity of Carbopol 940 0.3 %w/w with β-glucan 3 %w/w as compared to the commercial products (p>0.05). Carbopol 940 0.3 %w/w with β-glucan 3 %w/w has significantly less irritation than the commercial products (p <0.05). Conclusions: Type and amount of gelling agent affected the physical characteristics of gel base. However, the amount of β-